Catalog

Principles of Chemical Science

Chemistry MIT CC BY-NC-SA 4.0 36 lectures

This course provides an introduction to the chemistry of biological, inorganic, and organic molecules. The emphasis is on basic principles of atomic and molecular electronic structure, thermodynamics, acid-base and redox equilibria, chemical kinetics, and catalysis. In an effort to illuminate connections between chemistry and biology, a list of the biology-, medicine-, and MIT research-related examples used in 5.111 is provided in [Biology-Related Examples](/courses/5-111-principles-of-chemical-science-fall-2008/pages/biology-related-examples). ##### Acknowledgements Development and implementation of the biology-related materials in this course were funded through an HHMI Professors grant to Prof. Catherine L. Drennan. Videos and captioning were made possible and supported by the MIT Class of 2009.

Syllabus

  1. 1 Lecture 1: The Importance of Chemical Principles
  2. 2 Lecture 2: Discovery of Electron and Nucleus
  3. 3 Lecture 3: Wave-Particle Duality of Light
  4. 4 Lecture 4: Wave-Particle Duality of Matter
  5. 5 Lecture 5: Hydrogen Atom Energy Levels
  6. 6 Lecture 6: Hydrogen Atom Wavefunctions
  7. 7 Lecture 7: P-Orbitals
  8. 8 Lecture 8: Multielectron Atoms and Electron Configurations
  9. 9 Lecture 9: Periodic Trends
  10. 10 Lecture 10: Covalent Bonds
  11. 11 Lecture 11: Lewis Structures
  12. 12 Lecture 12: Ionic Bonds
  13. 13 Lecture 13: Polar Covalent Bonds and VSEPR Theory
  14. 14 Lecture 14: Molecular Orbital Theory
  15. 15 Lecture 15: Valence Bond Theory and Hybridization
  16. 16 Lecture 16: Thermochemistry
  17. 17 Lecture 17: Entropy and Disorder
  18. 18 Lecture 18: Free Energy and Control of Spontaneity
  19. 19 Lecture 19: Chemical Equilibrium
  20. 20 Lecture 20: Le Chatelier's Principle
  21. 21 Lecture 21: Acid-Base Equilibrium
  22. 22 Lecture 22: Chemical and Biological Buffers
  23. 23 Lecture 23: Acid-Base Titrations
  24. 24 Lecture 24: Balancing Redox Equations
  25. 25 Lecture 25: Electrochemical Cells
  26. 26 Lecture 26: Chemical and Biological Redox Reactions
  27. 27 Lecture 27: Transition Metals
  28. 28 Lecture 28: Crystal Field Theory
  29. 29 Lecture 29: Metals in Biology
  30. 30 Lecture 30: Magnetism and Spectrochemical Theory
  31. 31 Lecture 31: Rate Laws
  32. 32 Lecture 32: Nuclear Chemistry and Elementary Reactions
  33. 33 Lecture 33: Reaction Mechanism
  34. 34 Lecture 34: Temperature and Kinetics
  35. 35 Lecture 35: Enzyme Catalysis
  36. 36 Lecture 36: Biochemistry

Course materials