Catalog

General Biochemistry

Biology MIT CC BY-NC-SA 4.0 15 lectures

This course focuses on contributions of biochemistry toward an understanding of the structure and functioning of organisms, tissues, and cells. Topics include: - Chemistry and functions of constituents of cells and tissues and the chemical and physical-chemical basis for the structures of nucleic acids, proteins, and carbohydrates. - Basic enzymology and biochemical reaction mechanisms involved in macromolecular synthesis and degradation, signaling, transport, and movement. - General metabolism of carbohydrates, fats, and nitrogen-containing materials such as amino acids, proteins, and related compounds. NOTE: The first half of this course, taught by Prof. Yaffe, is available on the MITx platform as {{% resource_link "ecc701aa-4694-48fe-bf33-5234fe26ded2" "*7.05x Biochemistry: Biomolecules, Methods, and Mechanisms*" %}}. This OCW website provides content primarily from the second half with Prof. Vander Heiden, which focuses on metabolism.

Syllabus

  1. 1 Lecture 12: Carbohydrates/Introduction to Membranes
  2. 2 Lecture 19: Introduction to Metabolism/Polysaccharides/Bioenergetics/Intro Pathways
  3. 3 Lecture 20: Bioenergetics/Intro Pathways/Glycolysis I
  4. 4 Lecture 21: Glycolysis II/Regulation
  5. 5 Lecture 22: Glucogenesis/Carbohydrate Storage/TCA Cycle I
  6. 6 Lecture 23: TCA Cycle II
  7. 7 Lecture 24: Lipids and Fatty Acid Oxidation
  8. 8 Lecture 25: Oxidative Phosphorylation
  9. 9 Lecture 26: Oxidative Phosphorylation/Photosynthesis I
  10. 10 Lecture 27: Photosynthesis II/CO2 Assimilation
  11. 11 Lecture 28: Pentose Phosphate Pathway
  12. 12 Lecture 29: Lipid Synthesis
  13. 13 Lecture 30: Nitrogen/Amino Acid Metabolism I
  14. 14 Lecture 31: Amino Acid Metabolism II
  15. 15 Lecture 32: Nucleotide Metabolism

Course materials